Norris E Alderson

Editorial
Clin Trials 2005 2: 271-272. [PDF]  

Janet Woodcock

FDA introductory comments: clinical studies design and evaluation issues
Clin Trials 2005 2: 273-275. [PDF] [References]  

Robert Temple

How FDA currently makes decisions on clinical studies
Clin Trials 2005 2: 276-281. [PDF] [References]  

Steven N Goodman

Introduction to Bayesian methods I: measuring the strength of evidence
Clin Trials 2005 2: 282-290. [Abstract] [PDF] [References]  

Thomas A Louis

Introduction to Bayesian methods II: fundamental concepts
Clin Trials 2005 2: 291-294. [Abstract] [PDF] [References]  

Donald A Berry

Introduction to Bayesian methods III: use and interpretation of Bayesian tools in design and analysis
Clin Trials 2005 2: 295-300. [Abstract] [PDF] [References]  

Donald A Berry, Steven N Goodman, and Thomas A Louis

Floor discussion
Clin Trials 2005 2: 301-304. [PDF]  

Steven N Goodman and John T Sladky

A Bayesian approach to randomized controlled trials in children utilizing information from adults: the case of Guillain-Barre
Clin Trials 2005 2: 305-310. [Abstract] [PDF] [References]  

Joel B Greenhouse and Howard Seltman

Using prior distributions to synthesize historical evidence: comments on the Goodman–Sladky case study of IVIg in Guillain–Barré syndrome
Clin Trials 2005 2: 311-318. [Abstract] [PDF] [References]  

Larry Kessler, Joel B Greenhouse, Peter A Lachenbruch, Lawrence Gould, David Cornblath, and Russell Katz

Panel discussion of case study 1
Clin Trials 2005 2: 319-324. [PDF]  

Bailey Lipscomb, Guorong Ma, and Donald A Berry

Bayesian predictions of final outcomes: regulatory approval of a spinal implant
Clin Trials 2005 2: 325-333. [Abstract] [PDF] [References]  

Gregory Campbell, Celia Witten, Janet Wittes, Telba Irony, and Constantine Gatsonis

Panel discussion of case study 2
Clin Trials 2005 2: 334-339. [PDF]  

Andrew P Grieve and Michael Krams

ASTIN: a Bayesian adaptive dose–response trial in acute stroke
Clin Trials 2005 2: 340-351. [Abstract] [PDF] [References]  

Marc Walton, Richard Simon, Frank Rockhold, William DuMouchel, Garry Koch, and Robert O'Neill

Panel discussion of case study 3
Clin Trials 2005 2: 352-358. [PDF]  

Gregory Campbell

The experience in the FDA's Center for Devices and Radiological Health with Bayesian strategies
Clin Trials 2005 2: 359-363. [PDF] [References]  

Norris E Alderson (Moderator), Gregory Campbell, Ralph D'Agostino, Susan Ellenberg, Stacy Lindborg, Robert O'Neill, Don Rubin, and Jay Siegel

Statistical issues: a roundtable discussion
Clin Trials 2005 2: 364-372. [PDF]  

Janet Woodcock, Robert Temple, Karen Midthun, Daniel Schultz, and Stephen Sundlof

FDA senior management perspectives
Clin Trials 2005 2: 373-378. [PDF]  

To see an article, click its [PDF] link. To add articles to your marked citations, check the boxes to the left of the titles you want, and click the 'Add to Marked Citations' button. To see one abstract at a time, click its [Abstract] link.