Jisheng Cui, Andrew Forbes, Adrienne Kirby, Ian Marschner, John Simes, Malcolm West, and Andrew Tonkin

Parametric conditional frailty models for recurrent cardiovascular events in the lipid study
Clin Trials 2008 5: 565-574. [Abstract] [PDF] [References] [Request Permission]  

Kathryn E Flynn, Carrie B Dombeck, Esi Morgan DeWitt, Kevin A Schulman, and Kevin P Weinfurt

Using item banks to construct measures of patient reported outcomes in clinical trials: investigator perceptions
Clin Trials 2008 5: 575-586. [Abstract] [PDF] [References] [Request Permission]  

Andrew R Willan

Optimal sample size determinations from an industry perspective based on the expected value of information
Clin Trials 2008 5: 587-594. [Abstract] [PDF] [References] [Request Permission]  

Matthieu Resche-Rigon, Sarah Zohar, and Sylvie Chevret

Adaptive designs for dose-finding in non-cancer phase II trials: influence of early unexpected outcomes
Clin Trials 2008 5: 595-606. [Abstract] [PDF] [References] [Request Permission]  

Brent Logan, Eric Leifer, Chris Bredeson, Mary Horowitz, Marian Ewell, Shelly Carter, and Nancy Geller

Use of biological assignment in hematopoietic stem cell transplantation clinical trials
Clin Trials 2008 5: 607-616. [Abstract] [PDF] [References] [Request Permission]  

Franklin G Miller and Steven Joffe

Benefit in phase 1 oncology trials: therapeutic misconception or reasonable treatment option?
Clin Trials 2008 5: 617-623. [Abstract] [PDF] [References] [Request Permission]  

Kevin P Weinfurt

Varieties of uncertainty and the validity of informed consent
Clin Trials 2008 5: 624-625. [PDF] [References] [Request Permission]  

Michael Morse

Comment regarding benefit in phase 1 oncology trials
Clin Trials 2008 5: 626. [PDF] [References] [Request Permission]  

Nancy E Kass

Early phase clinical trials: communicating the uncertainties of `magnitude of benefit' and `likelihood of benefit'
Clin Trials 2008 5: 627-629. [PDF] [References] [Request Permission]  

FG Miller and S. Joffe

Response to Commentaries
Clin Trials 2008 5: 630. [PDF] [References] [Request Permission]  

Jonathan J Shuster, Douglas W Theriaque, and Brian M Ilfeld

Applying Hodges-Lehmann scale parameter estimates to hospital discharge times
Clin Trials 2008 5: 631-634. [Abstract] [PDF] [References] [Request Permission]  

Laurence S Freedman

An analysis of the controversy over classical one-sided tests
Clin Trials 2008 5: 635-640. [Abstract] [PDF] [References] [Request Permission]  

Marc Buyse

Reformulating the hazard ratio to enhance communication with clinical investigators
Clin Trials 2008 5: 641-642. [PDF] [References] [Request Permission]  

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